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Autism and Diet. Dr Nadeem Ghayas

April 12, 2025

Vitamins and nutritional supplements can play a supportive role in managing certain symptoms associated with autism, particularly when a child has underlying nutritional deficiencies. It is pertinent to mention here that vitamins are not a cure for autism. In addition each child with autism is unique, and the effectiveness of supplements can vary significantly from one individual to another. Several vitamins and supplements have shown some potential benefits when used carefully and under medical supervision.
Vitamin B6, often combined with magnesium, shows  improvement in communication, attention, and behavior in children with autism. Similarly, Vitamin D is frequently found to be low in individuals on the autism spectrum, and supplementing it can support brain health, mood regulation, and immune function. Omega-3 fatty acids, commonly found in fish oil, are also widely used due to their known benefits for brain development and behavior. Studies also suggest that omega-3s may help reduce hyperactivity and improve eye contact.
Now gut health. Gut health refers to the well-being of the gastrointestinal (GI) system, including the stomach, intestines, and colon, and its associated microorganisms, collectively known as the gut microbiome. It encompasses the functions of digesting food, absorbing nutrients, and eliminating waste. A healthy gut microbiome is crucial for overall health, influencing digestion, immunity, and even mental well-being.
 Many autistic experience digestive issues, and probiotics can help restore a healthy balance of gut bacteria, which may in turn influence mood and behavior. Multivitamins can also be helpful, especially for children who are picky eaters and may not get a balanced diet. Additionally, folate—especially in the form of methylfolate—may be beneficial for children with certain genetic profiles like the MTHFR mutation, which affects how the body processes folic acid.
Consulting professionals like  pediatricians, nutritionists, or autism specialists before introducing any vitamins or supplements is better. Medical guidance ensures that supplements are safe, appropriate, and tailored to the child’s individual needs. When used thoughtfully, and alongside evidence-based therapies such as speech, occupational, and behavioral therapy, vitamins can be part of a holistic approach to supporting children with autism.

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