Stanford Medicine researchers have made a very important discovery that could help people with autism in the future.
They found a way to reverse autism like behaviors in mice, meaning the mice started behaving normally again. This was done by calming down too much activity in a small but very important part of the brain called the reticular thalamic nucleus. This part of the brain works like a “gatekeeper” , controls how sensory information (like sound, touch, and sight) moves to other parts of the brain.
In people with autism, this system may not work properly, which can make them feel overwhelmed by sounds, lights, or touch. For a long time, scientists did not pay much attention to this part of the brain in autism studies, but this new research shows that it plays a key role.
The researchers used two methods to fix the problem:
1. A medicine that is usually given to control seizures (fits or epilepsy).
2. Neuromodulation, which is a gentle way of adjusting brain activity using electrical or chemical signals.
When they used these methods, the brain activity of the mice became balanced again, and the mice showed normal social and behavioral patterns. They became calmer and more responsive similar to how typical mice behave.
This research is also important because it found a strong connection between autism and epilepsy. Both conditions may involve the same brain circuits that control how signals travel through the brain. By studying these circuits, scientists can look for new ways to treat both disorders more effectively.
The findings give new hope for the future. Instead of only treating symptoms like speech delay or behavior problems, doctors might someday be able to treat the brain circuits directly that cause these issues.
In simple words, this discovery shows that autism might not always be a permanent condition , it could be improved or even reversed by calming certain parts of the brain. Although the study was done on mice, it opens a new door for research on humans and brings hope to millions of families living with autism.
Autism spectrum disorders (ASD) are a broad group of neurodevelopmental disorders that affect an individual’s social interactions, communication skills, and behavioral patterns.
The characteristics of ASD vary significantly between individuals, from mild social impairments to severe communication and behavioral problems, a diversity that reflects the use of the term “spectrum”. Although the exact causes of ASD are not fully understood, research suggests that both genetic and environmental factors play a key role in its development.
The Characteristics of ASD are as under
Difficulties in social interaction
Individuals with ASD often exhibit significant difficulties in social interactions. These difficulties may include difficulty understanding the feelings and intentions of others, maintaining eye contact and facial expressions, and adapting to social norms and expectations. Individuals with ASD may experience challenges in establishing and maintaining friendships, they may not understand the two-way nature of social interactions, or they may feel uncomfortable sharing interests and activities.
Communication disorders
Communication deficits are another core feature of ASD. This may manifest itself in delays in language development, including delays in uttering first words or simple sentences. Some individuals with ASD may not use language to communicate at all. Even among individuals with ASD who have normal language skills, they may have difficulty using language in conversations to communicate thoughts, feelings, or needs. In addition, nonverbal communication, such as the understanding and use of body language and facial expressions, may also be affected.
Repetitive behaviors and interests
Individuals with ASD often display restricted, repetitive patterns of behavior and interests. These may include a strong fixation on specific topics or activities, repetitive body movements (e.g., rocking, clapping), and an overreliance on daily routines. These repetitive behaviors are sometimes seen as a way of self-soothing or as an attempt to control an environment that otherwise feels unpredictable and overwhelming to them .
Sensory sensitivity
Many individuals with ASD have abnormalities in sensory processing and may have very strong or delayed responses to sound, light, touch, taste or odor. For example, some individuals with ASD may find background noises in their everyday environment unusually harsh, or they may not notice pain or other bodily sensations.
References
1. Cui M, Ni Q, Wang Q. Review of intervention methods for language and communication disorders in children with autism spectrum disorders. PeerJ. 2023;11: e15735.
2. Hirota T, King BH. Autism spectrum disorder: a review. JAMA. 2023;329(2):157–68.
3. Uljarević M, Phillips JM, Schuck RK, Schapp S, Solomon EM, Salzman E, Allerhand L, Libove RA, Frazier TW, Hardan AY. Exploring social subtypes in autism spectrum disorder: a preliminary study. Autism Res. 2020;13(8):1335–42.
4.Cheroni C, Caporale N, Testa G. Autism spectrum disorder at the crossroad between genes and environment: contributions, convergences, and interactions in ASD developmental pathophysiology. Mol Autism. 2020;11(1):69.
5. Morrison KE, DeBrabander KM, Jones DR, Faso DJ, Ackerman RA, Sasson NJ. Outcomes of real-world social interaction for autistic adults paired with autistic compared to typically developing partners. Autism. 2020;24(5):1067–80.
6. Baird G, Norbury CF. Social (pragmatic) communication disorders and autism spectrum disorder. Arch Dis Child. 2016;101(8):745–51.
- 7. Berry K, Russell K, Frost K. Restricted and repetitive behaviors in autism spectrum disorder: a review of associated features and presentation across clinical populations. Curr Dev Disord Rep. 2018;5:108–15.
Recently the Trump administration announced a $50 million Autism Data Science Initiative aimed at advancing research into the genetic, environmental, and medical contributors to autism. The initiative also proposed the creation of a national autism registry and efforts to accelerate approval of certain drug treatments, such as leucovorin for language delays in children with specific metabolic conditions. While these steps were presented as major commitments to autism research, they were accompanied by significant controversy.
Parents play a very important role in the life of their special need child. When parents support their child, the child feels safe, accepted, and encouraged to try new things.
Parents can help child educating their child, in daily activities or different therapies. There is no doubt that parents know their child better than anyone else means they understand the child’s strengths, needs, and feelings in a way no one else. Because of this so much understanding, parents can give the best support to their special need child. By being patient and kind, they make their child feel valued and capable.
Parents are prime educators. Parents also work with teachers and therapists to make sure their child gets the right help. They speak up for their child’s rights and provide guidance at home. This teamwork helps the child grow, learn, and become more independent. Parents love and care give the child strength and confidence. This confidence makes it possible to face the society.
Physiotherapists have an important role in special schools . They are healthcare professionals as well as a part of multiprofessional team of the school. There role is to work with children having physical and developmental challenges
As we know every child is different from other, so their needs are also different. Physiotherapists assess each student’s motor skills, muscle strength, posture, balance, and coordination. These detailed evaluations helps in understanding where a child may need support.
On the basis of assessments, they plan of each child aiming to improve mobility and daily living skills. These plans may include different exercises, stretching, or fun physical activities, tailored to the child’s specific abilities and goals. The crucial aim is to help children become as independent as possible in their daily living.
In many cases, physiotherapists also deal physical discomfort or pain. Physiotherapists do this by using techniques of pain management. These strategies also promote better posture and movement patterns to support long-term development.
In special need schools physiotherapists collaborate closely with special educators and other therapists such as occupational therapists, speech and language therapists, audiologists, and psychologists. This multi professional team builds a holistic plan that covers all aspects of a child’s development ie physical, emotional, cognitive, and social. Along with them parents, too, are an important part of child’s programme. Physiotherapists counsel and guide parents, helping them understand their child’s needs and how to support progress at home.
In conclusion, physiotherapist’s role in special need schools is very wide . They are assessors, planners, motivators, and partners in a child’s growth journey. Their work empowers children with special needs to participate more fully in school life and gain confidence in their own abilities.
Autism spectrum disorder is a neurological and developmental disorder that affects how people interact with others, communicate, learn, and behave. Although autism can be diagnosed at any age, it is described as a “developmental disorder” because symptoms generally appear in the first two years of life. People with autism have a wide range of symptoms, which can include differences in social and communication behaviors, intellectual disabilities, and other physical and mental health conditions. People with autism also have a wide range of health care and basic service needs. Research shows that access to needed services and supports early in life can promote people’s health and well-being over the long term.
Intelligence Quotient(IQ), is defined as a score that measures how a person’s thinking and problem-solving skills compare to others of the same age. IQ tests usually look at skills such as understanding language, memory, reasoning, and visual thinking. Some of the common IQ tests include the Wechsler Intelligence Scale for Children (WISC), the Stanford-Binet Intelligence Scales, and Raven’s Progressive Matrices. These tests were originally are for people without developmental conditions, so they may not fully capture the thinking styles of autistic children.
In the past, autism was often linked to intellectual disability. In the 1960s and 1970s, studies such as one by Rutter (1970) reported that up to 75% of autistic children had IQ scores below 70, which is considered to show an intellectual disability. This led many professionals, teachers, and families to believe that all autistic children had low intelligence. But this idea was based on tests that didn’t consider the unique ways autistic children learn and communicate. For example, nonverbal children couldn’t answer questions that relied on spoken words, and sensory issues like noise or bright lights often made it hard for them to focus. These tests also ignored areas where many autistic children are strong, like visual thinking or pattern recognition. As a result, many children were misjudged and misunderstood.
Today, research gives much clearer picture. A study conducted by Charman et al. (2011) found that only about 31% of autistic children have an intellectual disability. In contrast, 45% have average or even above-average IQ scores. Similar results were reported by the Centers for Disease Control and Prevention (CDC, 2020), showing that more and more autistic children are being identified without having intellectual disabilities. These changes are likely due to better testing tools and more awareness of the diversity within autism.
One of the most important things to understand is that autistic children often have uneven abilities. This is called a “spiky profile,” meaning they might be very strong in one area and struggle in another. For example, some children may have a low verbal IQ (trouble with language) but a high performance IQ, doing well on tasks that involve solving puzzles or recognizing patterns. Research using nonverbal tests like Raven’s Progressive Matrices has shown that many autistic children who score low on verbal tasks actually perform very well on visual tasks (Dawson et al., 2007). This highlights the importance of using a variety of tests to understand a child’s true potential.
There are many factors which affect how well an autistic child does on an IQ test. Communication is a major factor. Many autistic children are nonverbal or not compete with their age, they may not respond to questions that require spoken answers. They understand what they are told but not express what is expected.They also have sensory issues. It is seen that testing rooms with bright lights, background noise, or unfamiliar people can be awesome for autistic children, causing stress or distraction during the examination . If a child is uncomfortable , resultantly test scores may not reflect their true abilities.
IQ tests also include tasks based on social and language skills, like understanding a short story or identifying feelings from facial expressions. As the autistic children have problem in processing of information so these tasks may not match . Even a child is good at problem solving or logical thinking, they might score low on social-based questions. This can give a wrong impression of their overall intelligence. That’s why many experts recommend using flexible and personalized approaches to testing, so that each child’s strengths and needs are properly considered.
Another fascinating part of autism is the presence of splinter skills or savant abilities in some children. These are rare but amazing talents in areas like math, memory, music, or art. A child might struggle with everyday tasks but have an incredible memory or be able to play music by ear. Some can read at a very young age (a skill known as hyperlexia) or remember calendar dates for years into the future. These skills remind us that intelligence comes in many forms and can’t always be measured by a standard test (Treffert, 2009).
Understanding the different ways of thinking and learning of autistic children have big implications for education and therapy. It’s important for teachers and school professionals to create Individualized Education Plans (IEPs) that reflect each child’s specific abilities. Teaching strategies should focus on what a child can do, not just what they find hard. For example, using visual aids, assistive technology, or alternative communication tools can help children succeed in the classroom.
A strength- based approach can build confidence and help children reach their full potential. It’s also important that IQ should not only considered as the main measure of ability. Although IQ can provide useful information, it should not be the only factor when making decisions about diagnosis, support, or school placement. Instead, looking at a child’s adaptive functioning how they manage daily life, interact socially, and solve real-world problems can give a better picture of their abilities and needs.
References
- Charman, T., Pickles, A., Simonoff, E., Chandler, S., Loucas, T., & Baird, G. (2011). IQ in children with autism spectrum disorders: Data from the Special Needs and Autism Project (SNAP). Psychological Medicine, 41(3), 619–627.
- Dawson, M., Soulieres, I., Gernsbacher, M. A., & Mottron, L. (2007). The Level and Nature of Autistic Intelligence. Psychological Science, 18(8), 657–662.
- Lord, C., Brugha, T. S., Charman, T., Cusack, J., Dumas, G., Frazier, T., et al. (2020). Autism spectrum disorder. Nature Reviews Disease Primers, 6(1), 1–23.
- Rutter, M. (1970). Autistic children: Infancy to adulthood. Seminars in Psychiatry, 2(4), 435–450.
- Treffert, D. A. (2009). The savant syndrome: An extraordinary condition. A synopsis:past, present, future. Philosophical Transactions of the Royal Society B: Biological Sciences, 364(1522), 1351–1357.
- Centers for Disease Control and Prevention (CDC). (2020). Data & Statistics on Autism Spectrum Disorder.
Vitamins and nutritional supplements can play a supportive role in managing certain symptoms associated with autism, particularly when a child has underlying nutritional deficiencies. It is pertinent to mention here that vitamins are not a cure for autism. In addition each child with autism is unique, and the effectiveness of supplements can vary significantly from one individual to another. Several vitamins and supplements have shown some potential benefits when used carefully and under medical supervision.
Vitamin B6, often combined with magnesium, shows improvement in communication, attention, and behavior in children with autism. Similarly, Vitamin D is frequently found to be low in individuals on the autism spectrum, and supplementing it can support brain health, mood regulation, and immune function. Omega-3 fatty acids, commonly found in fish oil, are also widely used due to their known benefits for brain development and behavior. Studies also suggest that omega-3s may help reduce hyperactivity and improve eye contact.
Now gut health. Gut health refers to the well-being of the gastrointestinal (GI) system, including the stomach, intestines, and colon, and its associated microorganisms, collectively known as the gut microbiome. It encompasses the functions of digesting food, absorbing nutrients, and eliminating waste. A healthy gut microbiome is crucial for overall health, influencing digestion, immunity, and even mental well-being.
Many autistic experience digestive issues, and probiotics can help restore a healthy balance of gut bacteria, which may in turn influence mood and behavior. Multivitamins can also be helpful, especially for children who are picky eaters and may not get a balanced diet. Additionally, folate—especially in the form of methylfolate—may be beneficial for children with certain genetic profiles like the MTHFR mutation, which affects how the body processes folic acid.
Consulting professionals like pediatricians, nutritionists, or autism specialists before introducing any vitamins or supplements is better. Medical guidance ensures that supplements are safe, appropriate, and tailored to the child’s individual needs. When used thoughtfully, and alongside evidence-based therapies such as speech, occupational, and behavioral therapy, vitamins can be part of a holistic approach to supporting children with autism.
Hearing loss
According to WHO , an individual who is not able to hear as well as someone with normal hearing – hearing thresholds of 20 dB or better in both ears – is said to have hearing loss. Hearing loss may be from mild to profound. It can affect one ear or both ears and leads to difficulty in hearing conversational speech or loud sounds.
On the other hand, hard of hearing refers to people with hearing loss ranging from mild to severe. People who are hard of hearing usually communicate through spoken language and can benefit from hearing aids, cochlear implants, and other assistive devices as well as captioning.
Deaf people mostly have profound hearing loss, which implies very little or no hearing. They can benefit from cochlear implants. Some of them use sign language for communication.
Causes of hearing loss & deafness
Prenatal period
- genetic factors including hereditary and non-hereditary hearing loss
- intrauterine infections – such as rubella and cytomegalovirus infection.
Perinatal period
- birth asphyxia (a lack of oxygen at the time of birth)
- hyperbilirubinemia (severe jaundice in the neonatal period)
- low-birth weight
- other perinatal morbidities and their management.
Childhood and adolescence
- chronic ear infections (chronic suppurative otitis media)
- collection of fluid in the ear (chronic nonsuppurative otitis media)
- meningitis and other infections.
Adulthood and older age
- chronic diseases
- smoking
- otosclerosis
- age-related sensorineural hearing loss
- sudden sensorineural hearing loss.
Factors across the life span
- cerumen impaction (impacted ear wax)
- trauma to the ear or head
- loud noise/loud sounds exposure
- ototoxic medicines
- work related ototoxic chemicals
- nutritional deficiencies
- viral infections and other ear conditions
- delayed onset or progressive genetic hearing loss.
The impact of unaddressed hearing loss
Unaddressed, hearing loss impacts many aspects of life at individual level as under:
- limitations in communication and speech
- adversely affected cognition
- social isolation, loneliness and stigma
- impact on society and economy
- limitations in access to education and employment.
Prevention
Many of the causes that lead to hearing loss can be avoided through public health strategies and clinical interventions implemented across the life course.
Prevention of hearing loss is essential throughout the life course, from prenatal and perinatal periods to older age. In children, nearly 60% of hearing loss is due to avoidable causes that can be prevented through implementation of public health measures. Likewise, most common causes of hearing loss in adults, such as exposure to loud sounds and ototoxic medicines, are preventable.
Effective strategies for reducing hearing loss at different stages of the life course include:
- immunization
- good maternal and childcare practices
- genetic counselling
- identification and management of common ear conditions
- occupational hearing conservation programmes for noise and chemical exposure
- safe listening strategies for the reduction of exposure to loud sounds in recreational settings
- rational use of medicines to prevent ototoxic hearing loss.
Identification and management
Early identification of hearing loss and ear diseases is key to effective management.
This requires systematic screening for detection of hearing loss and related ear diseases in those who are most at risk. This includes:
- newborn babies and infants
- pre-school and school-age children
- people exposed to noise or chemicals at work
- people receiving ototoxic medicines
- older adults.
Hearing assessment and ear examination can be conducted in clinical and community settings. Tools such as the hearWHO app and other technology-based solutions make it possible to screen for ear diseases and hearing loss with limited training and resources.
Once hearing loss is identified, it is essential that it is addressed as early as possible and in an appropriate manner, to mitigate any adverse impact.
Rehabilitation for hearing loss
Rehabilitation helps people with hearing loss to function at their optimum, which means they can be as independent as possible in everyday activities. Specifically, rehabilitation helps them to participate in education, work, recreation and meaningful roles, for example in their families or communities, throughout their lives. Interventions for rehabilitation for people with hearing loss include:
- the provision of, and training in the use of, hearing technologies (e.g. hearing aids, cochlear implants and middle ear implants);
- speech and language therapy to enhance perceptive skills and develop communication and linguistic abilities;
- training in the use of sign language and other means of sensory substitution (e.g. speech reading, use of print on palm, Tadoma, signed communication);
- the provision of hearing assistive technology, and services (e.g. frequency modulation and loop systems, alerting devices, telecommunication devices, captioning services and sign language interpretation); and
- counselling, training and support to enhance engagement in education, work and community life.
Reference: WHO
The American Academy of Pediatrics (AAP) recommends autism screening at 18 and 24 months. Some children, however, especially those with mild symptoms, may not receive a diagnosis until school age or even adulthood. Early diagnosis is important because early intervention can significantly improve developmental outcomes.
Generaly the early signs of autism appear before the age of 2. Signs may include delayed speech and language skills, limited eye contact, lack of response to their name, and repetitive behaviors like hand-flapping or rocking. Children may also show unusual reactions to sensory stimuli, such as being overly sensitive to sounds or textures. Another common sign is difficulty in social interactions, such as not engaging in pretend play, not pointing to show interest, or not understanding facial expressions. Some children with Autism may also display an intense focus on specific objects or routines and become distressed with changes in their environment.
References
1. Centers for Disease Control and Prevention (CDC). (2023). Signs and Symptoms of Autism Spectrum Disorder.
2. American Academy of Pediatrics (AAP). (2020). Identifying and Evaluating Children With Autism Spectrum Disorders.
3. National Institute of Mental Health (NIMH). (2022). Autism Spectrum Disorder.